New issue · Mon 20 April

Audio Epilepsy Digest

A weekly audio briefing on epilepsy research.

On Air

In the current issue

Epilepsy care beyond the seizure count.

What should epilepsy care measure when seizure counts are not enough? This issue follows four recent papers across respiratory physiology, at-home EEG monitoring, patient-facing seizure terminology, and the lived burden of epilepsy for patients and caregivers.

The through-line is measurement humility: seizure counts remain essential, but they do not capture the whole clinical problem.

In this issueFour domains

  1. Respiratory variability after generalized convulsive seizures as a risk-signal domain, not a validated individual SUDEP prediction tool.
  2. At-home EEG self-monitoring as a feasibility signal for selected, supported patients.
  3. Patient-facing terminology for ictal impairment of consciousness, and the gap between comprehension and outcomes.
  4. Patient and caregiver burden beyond seizure frequency: mood, fatigue, sleep, productivity, and care-partner effects.

AI source review / Listen on Spotify

Back issues 2 issues

  1. No.02

    Weekly

    What seizure counts miss.

    Four blind spots that appear when epilepsy care is organized too narrowly around seizure counts: genetics after pediatric status epilepticus, early cognitive burden, drug-specific dose logic, and rescue-therapy endpoint design.

    In this discussion · 4 papers

    1. When pediatric status epilepticus should prompt a stronger genetics-first lens.
    2. What accelerated long-term forgetting shows, and does not show, about early memory burden.
    3. Why ASM dose-response ought to remain drug-specific rather than assumed uniform.
    4. Why the diazepam nasal spray SEIVAL paper matters more for endpoint design than immediate prescribing.

    Show notes & references / Listen on Spotify

  2. No.01

    Special

    Thalamic sEEG — standard of care, or research?

    A look at the February 2026 Brain debate cluster on thalamic stereoEEG, with focus on SEEG planning, neuromodulation targeting, safety, ethics, and institutional policy — without forcing false consensus.

    In this discussion · 5 perspectives

    1. Should thalamic recording be standard practice or IRB-approved research in stereoEEG?
    2. Is thalamic stereoEEG evaluation justified in routine clinical practice?
    3. Thalamic sEEG as a clinically justified extension of hypothesis-driven intracranial exploration.
    4. How thalamic stereoEEG optimizes neurostimulation therapy planning.
    5. The broader role of thalamic sEEG in epilepsy clinical practice.

    Show notes & references / Listen on Spotify

About the publication

Audio Epilepsy Digest turns recent epilepsy research into a single weekly audio brief for epileptologists. Episodes favor primary and authoritative sources, prefer full-text synthesis over abstract skimming, and stay explicit about the distinction between what a study supports and what it does not.

The show is an evolving collaboration between a human editor and AI co-hosts. Audio may misinterpret or oversimplify source material; the original published articles remain the authoritative reference for clinical decision-making. Corrections and feedback are welcome and directly shape future issues.