AED | Audio Epilepsy Digest Episode 004 Companion

AED Quiz

Drug-Resistant Epilepsy in 2026

Self-assessment questions on cenobamate-era surgical timing, ANT-DBS, and thalamic biomarkers.

This AED Quiz is for self-assessment and journal-club discussion. It is not accredited CME and does not provide CME credit.
EpisodeDrug-Resistant Epilepsy in 2026

Learning Objectives

  1. Separate surgical delay from surgical replacement in drug-resistant epilepsy pathways.
  2. Interpret palliative DBS evidence without treating it as seizure-freedom evidence.
  3. Identify why biomarker signals remain research-stage until prospectively validated.

Questions

1. What is the episode's practical synthesis about cenobamate and surgical evaluation?
Correct answer: B. The episode frames coexistence, not replacement: medication may change timing without obviating surgical evaluation.
2. How should the FRANCE ANT-DBS trial be framed?
Correct answer: B. The show note preserves the refractory cohort and palliative framing and avoids treating seizure-burden reduction as seizure freedom.
3. What is the safest use of Aiello's ANT spectral biomarker work today?
Correct answer: B. The episode treats the biomarker work as hypothesis-generating rather than ready for pathway decisions.

Reflection

What would change how you discuss this episode's evidence in journal club, clinic, or surgical conference?

Review Basis

Questions were drafted from the release show note, episode source-review boundary, and available episode planning materials. The page is intentionally framed as self-assessment, not accredited CME.