AED | Audio Epilepsy Digest Episode 021 Companion

AED Quiz

FCD: What Does the Diagnosis Actually Tell Us?

Self-assessment on integrated diagnosis, mosaicism, detection and treatment evidence.

This AED Quiz is for self-assessment and journal-club discussion. It is not accredited CME and does not provide CME credit.
EpisodeFCD: What Does the Diagnosis Actually Tell Us?
ReviewAI editorial/source review
ListenCanonical audio file

Learning Objectives

  1. Distinguish imaging, pathology and molecular findings.
  2. Recognize the limits of peripheral genetic testing.
  3. Interpret detection and treatment results within their study designs.

Questions

1. How should FCD type be interpreted?
Correct answer: C. The classification framework informs diagnosis; it does not by itself predict individual outcome or treatment benefit.
2. What does negative blood or saliva testing imply about brain-restricted mosaicism?
Correct answer: B. MTOR variants were not detected in the available blood or saliva samples in Lim’s study; negative peripheral testing does not exclude brain-restricted mosaicism.
3. What is the safest interpretation of an AI detection output?
Correct answer: A. Detection endpoints, controls and validation settings differ; model output is not a surgical map.
4. What did the overall everolimus comparison establish?
Correct answer: D. The reported primary comparison did not demonstrate superiority. Potential carryover, selection, sample size and harms limit practice implications; exploratory responses do not establish a treatment-selection rule.

Reflection

What would change how you discuss this episode's evidence in journal club, clinic, or surgical conference?

Review Basis

Questions were drafted from the release show note, episode source-review boundary, and available episode planning materials. The page is intentionally framed as self-assessment, not accredited CME.